Thursday, July 31, 2008

Launch of XTractor™ -a powerful scientific literature alert & abstraction system, now with unlimited free access.

Bangalore, India — Indian Life Sciences Informatics Company, Molecular Connections announced today, the release of XTractor™, a first of its kind manually curated literature alert service. XTractor™ can be accessed free of charge by the scientific community world wide.

XTractor™ acts as a literature alert service, which provides scientists with manually annotated scientific facts from literature. It enables researchers to be up-to-date with the latest scientific publications in the STM arena, as and when they are published. Once registered the scientists have the freedom to choose their keywords of choice and also set the frequency at which they wish to receive these alerts.

Mining scientific literature to retrieve accurate hits or extract entity relationship has always been a long-standing problem in research. It is a daunting task to identify the right gene name or the right drug name and extract relations/association with diseases, processes; pathways etc accurately form unstructured text. Text mining engines are fast enough but not accurate. XTractor™ with its efficient workflows combines the speed of a text-mining engine, with the accuracy of manual, expert curation.

XTractor™ is highly accurate and more efficient than many of NLP engines, since it is a hybrid model using technology and manual validation. Since the annotation is highly accurate researchers would also be able to perform complex queries and retrieve the most complex relations available in literature, which is currently not possible with the conventional NLP systems. Other than this XTractor™ acts as a platform for data sharing and categorization. Scientists can share their data with others and even tag data into customized datasets. Above all the data stored in one’s profile is accessible anytime, anywhere.

J Kamesh, Business Development Manager at Molecular Connections mentioned, “XTractor™ is a technology, which can and should be used by all life science researchers who want to stay current and updated in their field of interest. XTractor™ provides scientists with the ability to customize his own data needs. The researchers have the flexibility to change their keywords in tune with their changing research needs. The alerts get updated automatically for the new set of Keywords.”

To know more about the advantages of the XTractor™ and to register for a free trial account please logon to the Molecular Connections’ XTractor portal www.XTractor.in.

About Molecular Connections

Molecular Connections is a pioneering In silico discovery services company. It provides high quality, cost effective curation, literature informatics solutions and annotation services as well as products. Dr.Limsoon Wong is the Chairman of Molecular Connections. Customers of Molecular Connections include leading pharmaceutical and biotechnology, drug discovery, genomics, proteomics, medical technology, equipment companies and academic institutions spanning across the globe.





Be a part of the XTractor community. XTractor is the first of its kind - Literature alert service, that provides manually curated and annotated sentences for the Keywords of user preference. XTractor maps the extracted entities (genes, processes, drugs, diseases etc) to multiple ontologies and enables customized report generation. With XTractor the sentences are categorized into biological significant relationships and it also provides the user with the ability to create his own database for a set of Key terms. Also the user could change the Keywords of preference from time to time, with changing research needs. The categorized sentences could then be tagged and shared across multiple users. Thus XTractor proves to be a platform for getting real-time highly accurate data along with the ability to Share and collaborate.

Sign up it's free, and takes less than a minute. Just click here:www.xtractor.in.












Harnessing the power of multicore using PERL

How many of us really use our multi-core processors to the fullest extent? here is a blog article which gives some cool tips using PERL to exploit the power of your multi-core. I found this very interesting,


Be a part of the XTractor community. XTractor is the first of its kind - Literature alert service, that provides manually curated and annotated sentences for the Keywords of user preference. XTractor maps the extracted entities (genes, processes, drugs, diseases etc) to multiple ontologies and enables customized report generation. With XTractor the sentences are categorized into biological significant relationships and it also provides the user with the ability to create his own database for a set of Key terms. Also the user could change the Keywords of preference from time to time, with changing research needs. The categorized sentences could then be tagged and shared across multiple users. Thus XTractor proves to be a platform for getting real-time highly accurate data along with the ability to Share and collaborate.

Sign up it's free, and takes less than a minute. Just click here:www.xtractor.in.












Genes for schizophrenia uncovered

Three separate research projects have pinpointed genetic flaws linked to schizophrenia.

One of these, reported in the journal Nature, could mean a fifteen-fold increase in risk.However, one of the researchers warned that schizophrenia is so complex genes alone will only ever partially explain the illness at best. Scientists have suggested that an individual's risk of schizophrenia is roughly half dictated by their genetic make-up, and half by other factors during their lives. However, on both sides of this equation, much has still to be revealed about the precise causes. The three large-scale projects have taken a step towards unravelling the genetic picture of schizophrenia.

Do you want to know more?

Be a part of the XTractor community. XTractor is the first of its kind - Literature alert service, that provides manually curated and annotated sentences for the Keywords of user preference. XTractor maps the extracted entities (genes, processes, drugs, diseases etc) to multiple ontologies and enables customized report generation. With XTractor the sentences are categorized into biological significant relationships and it also provides the user with the ability to create his own database for a set of Key terms. Also the user could change the Keywords of preference from time to time, with changing research needs. The categorized sentences could then be tagged and shared across multiple users. Thus XTractor proves to be a platform for getting real-time highly accurate data along with the ability to Share and collaborate.

Sign up it's free, and takes less than a minute. Just click here:www.xtractor.in.












Wednesday, July 30, 2008

Biological Informatics

A Subject Tracer™ Information Blog developed and created by Internet expert, author, keynote speaker and consultant Marcus P. Zillman, M.S., A.M.H.A. for monitoring biological informatics (health informatics, neuroinformatics, biodiversity informatics and biomolecular informatics resources and sites on the Internet.

This blog page has a good, comprehensive listing of very handy useful bio web resource sites, the blog is divided into the following categories:

BIOLOGICAL INFORMATICS
HEALTH INFORMATICS (Medical Informatics)
NEUROINFORMATICS (NI)
BIODIVERSITY INFORMATICS (BDI)
BIOMOLECULAR INFORMATICS (BioInformatics)
Online Tools and Web Applications
Current Subject Tracer™ Information Blogs


Be a part of the XTractor community. XTractor is the first of its kind - Literature alert service, that provides manually curated and annotated sentences for the Keywords of user preference. XTractor maps the extracted entities (genes, processes, drugs, diseases etc) to multiple ontologies and enables customized report generation. With XTractor the sentences are categorized into biological significant relationships and it also provides the user with the ability to create his own database for a set of Key terms. Also the user could change the Keywords of preference from time to time, with changing research needs. The categorized sentences could then be tagged and shared across multiple users. Thus XTractor proves to be a platform for getting real-time highly accurate data along with the ability to Share and collaborate.

Sign up it's free, and takes less than a minute. Just click here:www.xtractor.in.












UK scientists have developed a drug which may halt the progression of Alzheimer's disease.

Trials of the drug, known as Rember, in 321 patients showed an 81% difference in rate of mental decline compared with those not taking the treatment.

The Aberdeen University researchers said the drug targeted the build-up of a specific protein in the brain.

Alzheimer's experts were optimistic about the results, but said larger trials were now needed.

Presenting the results at the International Conference on Alzheimer's Disease, Professor Claude Wischik said the drug may be on the market by 2012.

Do you want to know more?




Be a part of the XTractor community. XTractor is the first of its kind - Literature alert service, that provides manually curated and annotated sentences for the Keywords of user preference. XTractor maps the extracted entities (genes, processes, drugs, diseases etc) to multiple ontologies and enables customized report generation. With XTractor the sentences are categorized into biological significant relationships and it also provides the user with the ability to create his own database for a set of Key terms. Also the user could change the Keywords of preference from time to time, with changing research needs. The categorized sentences could then be tagged and shared across multiple users. Thus XTractor proves to be a platform for getting real-time highly accurate data along with the ability to Share and collaborate.

Sign up it's free, and takes less than a minute. Just click here:www.xtractor.in.










Tuesday, July 29, 2008

Blood Biomarkers for the Presence of Ruptured Atherosclerotic Plaques Identified

A research team from the University of Maastricht, The Netherlands, found biomarkers to detect the presence of ruptured atherosclerotic plaques. They observed that the blood of individuals with ruptured atherosclerotic plaques contained antibodies reactive against two peptides, E1 and E12.

The presence of these antibodies was detected extremely early after the onset of symptoms of a heart attack, according to the investigators. They caution, though, that further studies on additional patients are needed before this work can be translated into the clinic.




Be a part of the XTractor community. XTractor is the first of its kind - Literature alert service, that provides manually curated and annotated sentences for the Keywords of user preference. XTractor maps the extracted entities (genes, processes, drugs, diseases etc) to multiple ontologies and enables customized report generation. With XTractor the sentences are categorized into biological significant relationships and it also provides the user with the ability to create his own database for a set of Key terms. Also the user could change the Keywords of preference from time to time, with changing research needs. The categorized sentences could then be tagged and shared across multiple users. Thus XTractor proves to be a platform for getting real-time highly accurate data along with the ability to Share and collaborate.

Sign up it's free, and takes less than a minute. Just click here:www.xtractor.in.











Sunday, July 27, 2008

Molecular Connections perceives inorganic growth path

Molecular Connections, a life sciences informatics major, is now looking at acquiring small and medium-sized companies as part of its inorganic growth strategy.

"The acquisition will depend on good technology fit and domain expertise that could plug into our products and services,'' Jignesh Bhate, CEO, Molecular Connections Pvt Ltd told Pharmabiz.

"We are aggressively scouting for companies both in India and abroad. If we lay our hands on an international company, we will have access to their customers. In the case of an Indian company, we are essentially looking at a synergy in content and database,'' Bhate said.

To facilitate these acquisitions, Molecular Connections has identified three options to raise funds: internal accruals, foreign loans and venture funds. The mode of raising capital will depend on the size of the deal and the company is in talks with foreign banks. Around $2 million was raised from Barings Private Equity in 2006 for expansion.

Early this month, Molecular Connections was adjudged as the most promising company of the year by CNBC-ICICI for the Emerging India Awards out of more than 3.5 lakh entries.

The company, with sound financials, was also recognized as one of the fastest growing companies in the Technology Fast 50 India 2007 survey conducted by Deloitte Touche Tohmatsu, Asia Pacific. Molecular Connections was ranked 8th in India in the overall category.

The six-year-old company's product portfolio of informatics solutions focuses on protein interaction mechanisms of biological processes and also Biomarkers. Its maiden offering NetPro, the largest database globally on protein-protein has been upgraded with pharmacokinetics model. This is a market leader with repeat subscriptions from GSK, Aventis, Merck, Becton & Dickenson's bio-pharma unit and Galapagos NV, a drug discovery company.

The second product, CliPro's new version has been supplemented with biomarker data for clinical data. A recent product, Receptome is a comprehensive database of Functional Ligand-Receptor Complexes. Another new product, 'Xtractor' is a literature alert service, giving manually curated sentences of keywords as given by scientists.

All products are targeted at international customers because investments in informatics are increasing globally and the sector is getting its due importance. India pharma-biotech space will take a few years to utilize informatics' solutions offered from Molecular Connections, stated Bhate.

With collaborations helping to open a new dimension in research, Molecular Connections has partnered with the Bangalore-based Connexious Life Sciences for pathway work. Recently, it has teamed up with the Indian Institute of Science for a department of Biotechnology grant. The company's CYP database will be utilized by Prof P Kondaiah from the Department of Molecular Reproduction, Development & Genetics to customize drugs for the Indian population.

The global informatics market is valued at $6-8 billion. Of these four areas comprising validation & target identification, clinical development including toxicity studies, lead optimization studies, part of combinatorial chemistry is estimated at $6-8billion. Right now, Molecular Connections has the expertise in validation & target identification and is honing its skills in the area of ADME/TOX side and combinatorial chemistry.

Be a part of the XTractor community. XTractor is the first of its kind - Literature alert service, that provides manually curated and annotated sentences for the Keywords of user preference. XTractor maps the extracted entities (genes, processes, drugs, diseases etc) to multiple ontologies and enables customized report generation. With XTractor the sentences are categorized into biological significant relationships and it also provides the user with the ability to create his own database for a set of Key terms. Also the user could change the Keywords of preference from time to time, with changing research needs. The categorized sentences could then be tagged and shared across multiple users. Thus XTractor proves to be a platform for getting real-time highly accurate data along with the ability to Share and collaborate.

Sign up it's free, and takes less than a minute. Just click here:www.xtractor.in.