World's fastest growing Semantic discovery & Expert Curated Knowledgebase platform crosses 500,000 biomedical facts now

Indian Life Sciences Informatics Company, Molecular Connections announced today, that their XTractor Premium platform now has more that 503,985 "Expert" annotated biomedical facts from literature and is the fastest growing knowledgebase currently.

XTractor Premium platform is Fast Becoming the definitive Semantic Knowledge discovery & Expert curated Knowledgebase for Life Science Researchers. The XTractor Premium Knowledgebase in addition to more than 503,985 relationships on proteins, drugs, biological process and diseases has advanced semantic search, concept linking analytics for effective knowledge discovery and modeling.

XTractor Premium provides Precision based mining of the most relevant facts. Compared to natural language processing engines, manual annotation approach reduces false positives rate by 12-35%.

XTractor premium serves as a platform to stay current with weekly updates from PubMed. Provides “Topic Tracking” with email alerts on specific biological entities of interest via the “Watch List” feature.

The Highlights

Semantic Search: The first of its kind highly advanced search feature, where in one could query the XTractor Premium Knowledgebase using multiple ontologies. This would enable you to narrow down on your targets at ease.

Concept Linking: Our advanced query feature would enable you to make assumptions from multiple abstracts, and discover facts, which are hitherto not published.

Bibliographic search: Search based on author, organization, affiliation or country.

Save Export and Visualize: Save and export the data in user-friendly formats, also XTractor Premium is made compatible with CytoScape - so one can visualize the networks rendered using a in-house CytoScape plug-in.

Web based and onsite installation available

To know more about the advantages of the XTractor Premium and to register for a free trial account and a webex demo please visit XTractor Premium portal www.xtractor.in/premium.

About XTractor Premium Knowledgebase
XTractor knowledgebase currently contains 503,985 relationships on biomarkers, clinical trials, pathways, knockout studies, mutations, drug interactions, toxicity, pharmacokinetics, disease mechanisms. It is the Only Knowledgebase that gets updated everyday with manually annotated relationships from the latest PubMed publications and contains more than more than 1,269 Unique Drugs, 3,602 Unique Diseases, 11,407 Unique Proteins, and 3,266 Unique Biological Processes. Hence in no time one gets to access one of the largest and the most current manually annotated datasets across the world.

About Molecular Connections
Molecular Connections is a pioneering In silico Discovery Services Company. It provides high quality, cost effective curation, literature informatics solutions and annotation services as well as products. Dr. Limsoon Wong is the Chairman of Molecular Connections. Customers of Molecular Connections include leading pharmaceutical and biotechnology, drug discovery, genomics, proteomics, medical technology, equipment companies and academic institutions spanning across the globe. In addition, Molecular Connections has powerful tool development, database integration, effective data visualization capabilities, specific expertise in building knowledge bases for rapidly growing needs in, ADME Tox, clinical, drugs, chemistry and patent industries. For more information write to us at xtractorpremium@molecularconnections.com

Recent Awards
Deloitte Technology Fast 50 India Winners |Deloitte Technology Fast 500 APAC Winners |CNBC - ICICI Emerging India Awards ‘Small Enterprise of the Year’

XTractor Premium - A Platform for discovery, knowledge sharing, analysis and modelling of published biomedical facts.

• The only Knowledgebase which provides "manually" annotated facts from PubMed on a weekly basis
  
• Innovative Features like Semantic Search, Concept Linking, Bibliographic search, Save, Export and Visualize
  
• Only Knowledgebase with daily updations from PubMed
  
• XTractor Premium now at an Special Introductory Offer. Subscribe now and save!
  
• Request for a Trial
  

Entrez Gene outlink Integration for XTractor

Entrez gene is the most widely used data resource for Gene based information worldwide. To enable researchers to obtain high quality manually annotated information from XTractor when they search for a Gene on Entrez Gene, we are now providing direct links from Entrez Gene records to corresponding Gene Reports in XTractor.

To use this outlinked option- when in Entrez Gene, for any human gene select the “Link Out” option from the Display menu in Entrez Gene and click on the XTractor link. You will be taken directly to the XTractor graphical report for the Gene of interest and also manually annotated facts on the associated Diseases, Drugs and the Biological Processes for the Gene.

http://www.xtractor.in/ncbiSearch.do?xid=XT_15377&symbol=BRCA1

XTractor Premium - A Platform for discovery, knowledge sharing, analysis and modelling of published biomedical facts.

• The only Knowledgebase which provides "manually" annotated facts from PubMed on a weekly basis
  
• Innovative Features like Semantic Search, Concept Linking, Bibliographic search, Save, Export and Visualize
  
• Only Knowledgebase with daily updations from PubMed
  
• XTractor Premium now at an Special Introductory Offer. Subscribe now and save!
  
• Request for a Trial
  

The Perfect database to consult for SNP, Knockout/Knockdown related studies

Last week the XTractor Premium Knowledgebase has clocked 150,000 manually categorized biomedical facts.

The knowledgebase currently grows at a rate of more than 700 facts every single day from PubMed and covers information on Biomarkers, Disease mechanisms, Clinical Trials, polymorphisms, mutations, knockouts and pathways.

The knowledgebase recently crossed landmark of more 10000 relationships on knockout and mutation studies alone in XTractor.

• Knockout/Knockdown related facts: 10132
• Mutation related facts: 14331

So not only you get the most relavant scientific facts everyday but also individual uptodate knowledge on knockouts, mutations, biomarkers , SNP and so on…

XTractor Premium - A Platform for discovery, analysis and modelling of published biomedical facts.

• The only Knowledgebase which provides "manually" annotated facts from PubMed on a weekly basis
  
• Innovative Features like Semantic Search, Concept Linking, Bibliographic search, Save, Export and Visualize
  
• Only Knowledgebase with daily updations from PubMed
  
• XTractor Premium now at Introductory Offer of $450 for Academic Researchers. Subscribe now and save $300!
  
• Register for WebEx
  
• Request for a Trial
  
  

Pioneering Biomedical Web Community Poised For Leap To Web 3.0

The Alzheimer Research Forum (http://www.alzforum.org), a dynamic, biomedical Web community that is heavily used by Alzheimer researchers around the world, is preparing to migrate to a new platform that will enable it to more fully exploit social networking ("Web 2.0") and the Semantic Web ("Web 3.0"). Founded 13 years ago when the Web was still in its infancy, the "Alzforum" has more than 5,000 registered members and is familiar to most Alzheimer scientists in the world.

Ever since launching in 1996, the Alzforum Web site has been interactive, posting researchers' comments on published papers and research news. The site has published thousands of peer commentaries and mini-reviews by leading scientists in the field, and has established itself as the "go to" Web site for anyone who wished to be up to date on Alzheimer research. Members can post commentaries on any journal article or news story, and can participate in live discussion forums. Researchers frequently reference Alzforum in scientific papers and conduct weekly "Alzforum" sessions in their labs to discuss current findings. The AlzGene database, designed and curated by researchers at Massachusetts General Hospital and developed and hosted by Alzforum, is a workhorse of the global genetic community, and has generated a primary research publication in Nature Genetics. Alzforum has built numerous other data resources for the research community.

This spring, Alzforum will re-develop its site using the Scientific Collaboration Framework (SCF), a project based on open-source Drupal technology that is designed for building scientific Web communities. SCF was piloted by the Harvard Stem Cell Institute to build a Web publication called StemBook (www.stembook.org). Alzforum will develop some new software modules in Drupal and contribute them back to the SCF, where they will be freely available for other research organizations that are building their own Web communities. (SCF software is available at http://www.sciencecollaboration.org).

SCF is well-suited for publishing articles, comments, forums and blogs, and for managing member communities with fine degrees of editorial control. "We want it to be very easy for anyone to participate, but it's also essential for our editors to vet all postings in order to maintain civil and productive discourse," says Alzforum's co-founder and Executive Editor June Kinoshita.

A feature of SCF that Alzforum's editors are excited about is a semantic tagging module that locates scientific terms within an article, such as names of genes, organisms, and biological processes, and proposes them as tags that describe key concepts in the article. The tags enable the user to search other content with matching or related tags, so that an article about a gene can be automatically linked to a description of the gene, to articles about the gene, and even to the profiles of scientists who study that gene.

"The possibilities this opens up for scientists to navigate a knowledge network of articles, databases, and people is amazing," says Kinoshita. "And all of the Web communities that share the SCF platform will be interconnected. Alzforum has always been about building a research community without walls. Using the SCF, we will take this idea to a whole other level."

• XTractor Premium - a Platform for, discovery, analysis and modelling of published biomedical facts
  
• The only Knowledgebase which provides "manually" annotated facts from PubMed on a weekly basis
  
• Innovative Features like Semantic Search, Concept Linking, Bibliographic search, Save, Export and Visualize
  
• Only Knowledgebase with daily updations from PubMed
  
• XTractor Premium now at Introductory Offer of $450 for Academic Researchers. Subscribe now and save $300!
  
• Register for WebEx
  
• Request for a Trial
  
  

Gel for Controlled Drug Delivery

Massachusetts Institute of Technology (MIT) researchers have demonstrated that a gel composed of small, woven protein fragments can successfully carry and release proteins of different sizes, potentially enabling the delivery of drugs such as insulin and trastuzumab (Herceptin).

Researchers can control the rate of release by changing the density of the gel, allowing for continuous drug delivery over a specific period of time. The team is led by Shuguang Zhang, associate director of MIT's Center for Biomedical Engineering.

The gel, known as a "nanofiber hydrogel scaffold," enables a gradual release of the proteins from the gel over hours, days or even months. The gel itself is eventually broken down into harmless amino acids - the building blocks of proteins. Peptide hydrogels are ideally suited for drug delivery as they are pure, easy to design and use, non-toxic, non-immunogenic, bio-absorbable, and can be locally applied to a particular tissue.

Composed of self-assembling amino acid chains (peptides), the gel is about 99 percent water by volume. Depending on the size and density of the mesh, it can carry protein molecules between 14,000 and 150,000 daltons (a unit of molecular weight). Trastuzumab, an antibody protein often used to treat breast and ovarian cancer under the brand name Herceptin, is about 50,000 daltons. Researchers also showed that proteins carried by the gel emerge unscathed after delivery, with no adverse affect on their function.

Potential applications include delivery of insulin, monoclonal antibodies such as Herceptin, hormones, growth factors and cancer drugs, as well as eye medications.

Be part of XTractor community.

• XTractor the first of its kind - Literature alert service, provides manually curated & annotated sentences for the Keywords of your choice
  
• XTractor maps, extracted entities (genes, processes, drugs, diseases etc) to multiple ontologies
  
• Enables customized report generation. With XTractor the sentences are categorized into biologically significant relationships
  
• The categorized sentences could then be tagged and shared across multiple users
  
• Provides users with the ability to create his own database for a set of Key terms
  
• Users could change the Keywords of preference from time to time, with changing research needs
  
• XTractor thus proves to be a platform for getting real-time highly accurate data along with the ability to Share and collaborate
  
  

Sign up it's free, and takes less than a minute. Just click here:www.xtractor.in.

A cool ready reckoner on Drugs, Dieases, Proteins & Processes

XTractor now has a ready reckoner on Drugs, Diseases, Proteins & Processes along with sample manually annotated sentences form PubMed available on each of those Drugs, Diseases, Proteins & Processes listed there. This is really going to be handy for any bench scientist.

Be part of XTractor community.

• XTractor the first of its kind - Literature alert service, provides manually curated & annotated sentences for the Keywords of your choice
  
• XTractor maps, extracted entities (genes, processes, drugs, diseases etc) to multiple ontologies
  
• Enables customized report generation. With XTractor the sentences are categorized into biologically significant relationships
  
• The categorized sentences could then be tagged and shared across multiple users
  
• Provides users with the ability to create his own database for a set of Key terms
  
• Users could change the Keywords of preference from time to time, with changing research needs
  
• XTractor thus proves to be a platform for getting real-time highly accurate data along with the ability to Share and collaborate
  
  

Sign up it's free, and takes less than a minute. Just click here:www.xtractor.in.